Jeans for Genes

One in 20 children is born with some kind of congenital abnormality or genetic disease.

Jeans for Genes is a major national fundraiser of the Children’s Medical Research Institute (CMRI). Since 1994, millions of Australians have raised more than $56 million through Jeans for Genes to support research at Children’s Medical Research Institute across four key areas: cancer, embryology, gene therapy and neuroscience.

Every child deserves a chance at a healthy future.

Children’s Medical Research Institute conducts pioneering research to understand the genes important for health and development, and the underlying causes of diseases.
By studying the key changes that occur during a child’s early development, we may be able to reduce the impact of disease on our children’s quality of life, or better yet, prevent disease altogether.

Many diseases that affect children, such as cancer and epilepsy, have the same basic origins in adults. This means our research has the potential to improve the future health of men, women and children across the nation – and the rest of the world – for generations to come.

World Class Research

Children’s Medical Research Institute’s great strength lies in its independence and ability to se4t its own research agenda. Our researchers have international recognition for excellence in four key areas of research:

• Cancer
CMRI has three cancer research laboratories that investigate characteristics of cancer that are different from normal cells, especially the ability of cancer cells to continue multiplying an unlimited number of times. The aim of this research is to find treatments that specifically kill cancer cells in the any type of cancer but spare normal cells, and therefore have fewer side-effects than the cancer chemotherapies that are currently available.

• Embryology
We study how embryos develop normally, so that we can understand what has gone wrong when children are born with abnormalities. This lays the foundation for early diagnosis, treatment and prevention of a variety of birth defects.

• Neuroscience
We study a key aspect of how nerve cells communicate with each other, especially in the brain. This is critically important for developing new forms of treatment for conditions such as epilepsy.

• Gene Therapy
Many childhood diseases are caused by inheriting a damaged copy of a particular gene. CMRI researchers are developing the capability to treat some of these conditions by delivering normal copies of the damaged genes directly into the affected cells of the diseases tissues.

For more information visit www.cmri.org.au

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